Institute
of Molecular Biology & Biotechnology
Institute
of Molecular Biology and Biotechnology (IMBB),
The University of Lahore, was established in 2004.
It started academic programmes of postgraduate
teaching and research degree leading to M. Phil.
and Ph. D. in the subjects of biochemistry, physiology
and molecular biology and biotechnology. Later
M. Sc. and B.Sc Hons (4 year) degrees were also
added. It is the first institute of its kind established
in the private sector. It fulfills the requirements
for advancements in the subjects of biological
sciences, which is now the most important area
of studies for the 21st century associated to
economic and industrial development of the country.
Efforts are under way to upgrade the existing
facilities at the IMBB to the status of a centre
of excellence.
The subjects
of biochemistry and Molecular Biology have emerged
new trends in molecular biology & biotechnology
Curricula with special emphasis on cellular mechanism
leading to function in living organisms. The institute’s
focus was designed on these areas in conjunction
to developments in recombinant DNA technology,
monoclonal antibody, immunology, immunoassays
and protein sequencing etc, to study the structural
and functional aspects is of specific importance.
These basic and applied research fields have helped
to explore innovative pathways of research fields
to understand genomics and proteomics. At present
this institute is actively engaged in studies
related to male infertility, cell receptor studies,
lipid-membrane-receptors interactions, cancer,
molecular detection of infectious diseases, application
of immunoassays in diagnostic fields & industrial
uses.
Degrees Offered
a) Bachelor of Science (Honors)
- 4years
b) Master of Science
c) Master of Philosophy
d) M. Phil Leading to Doctorate of Philosophy
e) Doctorate of Philosophy
All degrees offered with specialisation in either;
Biochemistry or Molecular Biology & Biotechnology
or Physiology.
B.Sc
Hons (4 years program)
The four-year degree programme
in biochemistry consists of 8 semesters comprising
of 18 weeks each. This includes 16 weeks teaching
and 2 weeks for examination etc. There be 2 semesters
comprising of a winter semester (January – May)
and a Fall Semester (August – December). Short
summer semester comprising of 8 weeks each year
to take failed courses and specified new courses.
A student with biochemistry major may opt for
two of the three minor subjects i.e. physiology,
microbiology & chemistry. Each minor subject
will comprise of 12 credit hours. In addition
to the major and minor subjects it will be mandatory
for every student to take Islamiat, Pakistan Studies,
English, Mathematics, Statistics and computer
science courses as prescribed in university calendar.
The total number of these compulsory courses will
not be exceeding 24 credit hours. In total 134
credit hours are required with minimum CGPA of
2.0 (60% or C grade) and no F Grade.
Scheme
of studies for B.Sc. Hons (4 years program)
Semester-wise Course plan for B.Sc. Hons four
years program in Biochemistry
Duration: 4 years (8-semesters)
Combinations of minors (planned for session 2006-10)
Group I: Physiology & Microbiology
Group II: Microbiology & Chemistry
Group III: Physiology & Chemistry
Semester 1
Introductory Biochemistry
Fundamentals of Microbiology
Fundamentals of Physiology
Introduction to Computer Science
English Comprehension I
Islamic Studies
Semester 2
Biochemistry of Macromolecules
Biology of Micro-organisms
Human Physiology
English Comprehension II
Biomathematics I
Pakistan Studies
Semester 3
Metabilism of carbohydrates
Biosynthesis of Amino acids
Enzymology I
Medical Microbiology I
Blood and body fluids
Semester 4
Microbial Biochemistry & genetics
Molecular Biology I
Biochemical Techniques
Bioengergetics
Medical Microbiology II
Neuromuscular Physiology
Semester 5
Plant Biochemistry
Recombinant DNA I
Medical Biochemistry
Immunochemistry
Transpot through membranes
Semester 6
Recombinant DNA II
Bioinformatics
Expression & transmission of genetic information
Introduction to research methodologies
Plant & Industrial Biotechnology
Semester 7
Immunology
Biochemical Communications
Introduction to genetic engneering
Enzymology II
Special problem
Seminar
Microbiology II
Seminar 8
Cell & Tissue Culture
Industrial Enzymology
Enviornmental Biotechnology
Microbial Biochemistry & Genetics
Fundamental Endocrinology
Special Problem
MSc
Programmes
The institute has initiated
two-year M. Sc. programs in Physiology, Biochemistry,
and Molecular Biology & Biotechnology, which
will be covered in 4 semesters spreading over
2 years. This comprises of two summer sessions.
Each semester will be of 18 weeks duration - 16
weeks for teaching and two week for conduction
of examination etc. The 1st semester (Fall) will
start in 1st week of August while the 2nd (Winter)
will commence from 1st week of January as notified
in university calendar. There will be a short
summer of 8 weeks would be offered for failed
courses or other courses. The summer term will
start from 1st June to 31st July. The 2nd semester
onwards the student will pursue studies in various
disciplines specializing categorically in physiology,
biochemistry, molecular biology & biotechnology.
The student will also take research on selected
topics and write a thesis in 4th semester. In
addition to the learning process, the research
project, practical training, study visits, assignment,
presentations, discussions are integral and essential
part of the training programs.
Admissions,
Eligibility and Registration
Students seeking admission to M. Sc. program must
fulfill the following eligibility criteria:
1. Applicant for M. Sc. studies must have passed
graduation or equivalent examination in the relevant
field from a recognized university, at least 2nd
Division / C grade or must hold B. Sc. (in relevant
fields) or MBBS/ BDS/ DVM/ B. Pharmacy degree(s)
& B. Sc. (Laboratory Technology).
2. All applicants will be subjected to written
test followed by an interview with the Advisory
Committee of the Institute.
3. Applications for admission will be made on
a prescribed form available from the Admission
Office of the University.
4. Those accepted for admission will be notified
accordingly within two days of the holding of
the test.
5. The selected students will be required to register
themselves with the Office of the Registrar within
one week and clearing the semester/registration
fee applicable thereof.
6. Classes will start as may be notified by the
Director of the Institute.
Teaching
Methodologies
Apart from the specified
curriculum for M. Sc. degrees the institute will
provide a stimulating environment for learning
through efforts of motivated teachers. Programs
are devised and implemented to allow high level
of scholaristic attainment.
Teaching methodologies emphasize promotion of
student’s learning and comprehension of the subject
matter. As far as possible particular attention
will be given to the application of the principles
of basic and applied learning. The methodologies
employed for teaching shall emphasize development
of skill of (a) independent learning (b) critical
analysis, comprehension and solving of scientific
problems, (c) work planning and execution, and
(d) communication through written, oral, and electronic
media. Thus in addition to lecture work, problem
solving exercises, assignments, discussions, and
student seminars, research and thesis will form
a central part of each program.
Scheme
of Studies and Courses offered by the Institute
The Academic year will comprise
of two semesters of 18 weeks each including teaching,
Laboratory work and examinations, as may be prescribed
by the institute. One summer semester of 8 weeks
will be allocated to repeat, failed courses or
improvement of GPA less than 2.5.
• During the first two semesters, the students
shall have to pass the prescribed courses (equal
to 24 credits) with a minimum cumulative G.P.A.
of 2.5.
• At the end of 2nd semester, on the completion
of course work (24 credit hours), the student
will submit a synopsis for the research project
to be undertaken for M. Sc. as the case may be,
under the guidance of his / her research thesis
perspective supervisor.
• The Advisory Committee of the Institute shall
approve the synopsis.
• Subsequent to the approval of the research project,
the student will be assigned a supervisor for
the thesis research work to be undertaken by him
/ her duly recommended by the Departmental Academic
committee (DAC).
List
of courses for MSc degree
MSc – Biochemistry
Principles of biochemistry
Recent advances in biochemistry
Comparative Biochemistry
Introduction to immunology
Biochemistry and diseases
Chemotherapy and radiotherapy
Cell Biology
Membrane structure and transport
Neurochemistry
Hormones in human life
Protein Structure, function, and synthesis
Environmental biochemistry
Nutrient utilization
Instrumentation and analytical techniques
Principles of statistics
Special problem 1
Seminar 1
Research & Thesis
MSc - Molecular Biology & Biotechnology
Introduction to molecular biology & Biotechnology
Advance Molecular Biology
Resource biotechnology
Industrial Enzymology
Food and waste biotechnology
Molecular Biology and recombinant DNA
Molecular Pathogenesis
Use of molecular biology in disease diagnosis
Principles of chemical and biochemical engineering
Environmental Biotechnology
Safety consideration for biotechnology
Antimicrobials and Chemotherapy
Principles of Microbiology
Instrumentation and analytical techniques
Principles of statistics
Special problem
Seminar
Research & Thesis
MSc – Physiology
Introduction to Physiology
Principles of Molecular Physiology
Nutrient digestion and utilization
Recent Advances in human Physiology
Physiological Chemistry
Neuromuscular and endocrine Physiology
Cardiovascular Physiology and circulation
Respiratory and renal Physiology
Cell Physiology
Physiology of steroid Hormones
Comparative experimental Physiology
Enzymology
Physiology of skin, hair, and nails
Physiological techniques
Principles of statistics
Special problem
Seminar
Research & Thesis
Note
Every M. Sc. student will take 24 credit hours
of course work and 15 credit hours of research
and thesis (100 marks). The statistic (615) will
be compulsory in each discipline. The student
will be allowed maximum of 12 credit hours of
courses in a semester in addition to research
and thesis. During the summer semester the students
will only be allowed to repeat failed courses
or improve grade point average (GPA) of C grade,
or less. The special problem and seminar will
also be compulsory in each discipline.
Courses have been designed to enable students
to gain recent knowledge and hands-on experience
in important areas of research. This is supported
by the approach that one year of course work covering
upto 24 credit hours and 15 credit hour research
works in 2nd year with special problems and seminar
and/ or any other left over course. The delivery
of courses is based on lectures, seminars, problem
tackling, review writing, discussions and interactive
learning. The DAC of the Institute guides each
student to develop an academic road map, since
several options in each discipline will be available.
Arrangements are available to interact with the
supervisor and other faculty members directly
or through Internet. The Institute takes a holistic
approach to the delivery of curriculum and experimental
work. Most of the courses, as listed elsewhere,
are based on theory and practicals with a view
to impart broader vision of the subject.
M.Sc. program: 24 Cr. Hrs (course work) + 15 Cr.
Hrs. (Research and thesis) = 39 Cr. Hrs
M.
Phil. leading to Ph. D programmes
Introduction
The Institute of Molecular Biology and Biotechnology
has been established by The University of Lahore
with the specific purpose of undertaking advanced
research at M. Phil and Ph. D. along with other
programs. The institute has also started program
of M. Phil. leading to Ph. D. degree. The institute
has made arrangements to teach, train research
scholars to acquainted themselves with state of
the art technologies including amplification methodologies,
separation technologies, animal studies etc. to
undertake research at the highest level. Entry
to M.Phil/ Ph.D program will be subjected to clearing
GRE (local or international).
Meticulous stress is placed on applied research
related to economic development of the country,
in the field of health, agriculture, and industry,
which is in agreement with the research priorities
fixed by the government. A rigorous program of
education and training has been developed in order
to produce manpower, which could be absorbed well
in the local environment
Core Courses for 1st Year
(24 Credit Hours)
a. Compulsory a. Compulsory Biostatistics
b Optional
Scheme
of Studies and Courses offered by the Institute
1. The Academic year will comprise of two semesters,
the Institute may prescribe each of 18 weeks including
teaching, laboratory work and examinations.
2. During the first two semesters, the students
shall have to pass the prescribed courses (equal
to 24 credits) with a cumulative G.P.A. of 3.0
or greater or as advised.
3. The provision of section 2 above is applicable
both to M.Phil and Ph. D. students. The students
who convert their program from M. Phil leading
to Ph. D. will take 18 credit hours of additional
teaching to complete his / her course work.
4. At the end of 2nd semester, on the completion
of course work of 24 / 42 credit hours, the student
will submit a synopsis of the research to be undertaken
for M.Phil or Ph.D. as the case may be.
5. The synopsis after approval of the Advisory
Committee (AC) of the Institute shall be forwarded
to the Registrar for submission to the Board of
Advanced Studies and Research for approval of
the topic of the thesis.
6. Subsequent to the approval of BASR, the student
will be assigned a supervisor for the thesis work
to be undertaken by the student.
7. Students of M.Phil in relevant field will be
exempted 24 Credit Hrs of M.Phil but may be given
deficiencies of 18 credit hours for Ph.D.
Courses of Study for M. Phil, M. Phil leading
to Ph.D and Ph. D. to be offered by the Institute
Biochemistry
courses
Introduction to biochemistry; molecules, cells
& organisms
Biostatistics
Advanced microbial genetics
Advancements in protein structure function relationships
Classification and metabolism of lipids &
carbohydrates
Classification and metabolism of nucleic acids
DNA synthesis and genetic disorders
Biochemical basis of gene expression and regulation
Recent advancements in recombinant DNA technology
Techniques in biochemistry
Biochemical basis of cancer
Recent advancements in immunology
Recent advancements in enzymology
Advanced endocrinology
Bioenergetics & Oxidative Phosphorylation
Nutrition & dietetics
Biochemical basis of cell signaling & signal
transudation cascades
Biochemical basis of diseases
Biochemistry of blood
Special problem
Seminar on thesis topic
Research and thesis M.Phil & Ph.D
Molecular Biology
and biotechnology
Introduction to molecular biology & biotechnology
Biostatistics
Recent advances in molecular biology and Biotechnology
Nucleic acid structure and function
Molecular basis of cancer
Molecular biology of genetic disorders
Gene expression and regulation
Stem cell research
Chromosomal mapping & its applications
Techniques in molecular biology & biotechnology
Molecular immunology
Principles and applications of biotechnology
Recent advancements in industrial enzymology
Molecular biology and pedigree identification
Environmental biotechnology
Agricultural waste biotechnology
Genetic engineering; methods & applications
Recombinant technology
Applications of biotechnology in medicine
Special problem
Seminar on thesis topic
Research and thesis M. Phil & Ph. D
Physiology
courses
General physiology
Biostatistics
Advances in nervous system physiology
Physiology of digestion
Physiology of nerve and muscle
General endocrinology & pituitary hormones
Physiology of adrenals, pancreatic, thyroid &
parathyroid hormones
Respiratory & space physiology
Reproductive physiology
Physiological techniques
Physiology of liver & reticulo-endothelial
system
Renal physiology & body fluids
Physiology of skin & thermoregulation
Advanced physiology of blood
Recent advances in physiology
Physiology of special senses
Physiology of body defense mechanisms
Physiological basis of molecular biology
Cell Physiology
Special problem
Seminar on thesis topic
Research and thesis M. Phil & Ph. D
Note: Each student registered for M.Phil/Ph.D.
program shall have to complete 24 credit hours
(16 credit hours in major subjects and 8 credit
hours in the minor subject.) The selection of
courses can be made after consultation with the
Advisory Committee of the Institute.
REGULATIONS
FOR Ph.D. DEGREE (2002) (Revised)
Under Section 16 of the University Ordinance No.
LXI of 2002.
Submission of Thesis
1. The topic of the thesis will be proposed by
the supervisor and recommended by the Director
for obtaining final approval from BASR through
Registrar of the University.
2. On completion of thesis, the Director of the
Institute will recommend appointment of supervisor,
in consultation with the AC.
3. The maximum period allowed for submission of
thesis for M.Phil if not proceeding to Ph.D. program
will be 3 years and for Ph.D. it will be five
years from the date of registration.
4. The candidate who are not graded fit (who secures
CGPA of less than 3.0) for continuation to Ph.D.
degree will be allowed another 1-2 years for research
thesis and will be awarded M.Phil degree on satisfactory
performance. Only those students of M.Phil who
obtain a CGPA of 3.0 will be allowed to transfer
to Ph.D. program and will take another 18 credit
hours in his major field (those with CGPA 2.5
or more will be eligible for M.Phil degree).
5. A candidate shall be eligible to submit thesis
at the end of the 2nd year for M.Phil and at the
end of 3rd year for Ph.D. degree from the date
of admission. Subject to GRE clearance (local
or international in 2 attempts)
6. Total credit hours:
I. M.Phil 24 (course work) + 20 (research and
thesis) = 44
II. M. Phil leading to Ph. D. 42 + 30 (research
and thesis) = 72
III. Ph.D. 18 (course work) + 30 (research and
thesis) = 48
Evaluation of Thesis
Examination Committee
In case of Ph. D. on receiving the thesis through
the Controller of Examinations, the Chairman BASR
on the recommendation of the Head of AC will appoint
3 (three) examiners, one of whom shall be the
research supervisor as the internal examiner and
2 (two) overseas external examiners.
According to the recommendations
of the above-mentioned examiners the candidate
will defend his/her thesis in the presence of
a committee constituted by the Rector comprising
of 5 persons including Director of the Institute
and supervisor of the candidate. The Rector of
the University from within the country will nominate
the other three examiners.
If all the three examiners give an adverse opinion
about the Ph. D. thesis, it shall be rejected.
If two of three recommend the thesis for the award
of degree and one disagrees, a fourth examiner
shall be appointed by the Chairman BASR, and the
opinion of the fourth examiner shall be final.
In case of M. Phil, the supervisor (internal examiner)
and an external examiner (local) from a panel
of three proposed by the AC will be appointed
by the Chairman BASR will examine the thesis
Defense of Thesis
A candidate for Viva examination shall apply to
the Controller of Examination on the prescribed
Form along with five (05) copies for M. Phil.
and nine (09) copies of thesis for Ph.D and a
certificate from his/her supervisor, duly countersigned
by the concerned Head of the Department that the
rules and regulations about the format of the
thesis have been followed.
The Viva Voce Examination will be held at a place
and on a suitable date as may be determined by
the Rector. Each of the examiners shall submit
the report independently to the Chairman BASR
and make one of the following recommendations:
i. that the Viva Voce examination be held to enable
the candidate to defend his/her thesis;
ii. that the thesis be resubmitted by the candidate
after revision on the lines to be suggested by
the examiner(s);
iii. that the thesis be rejected being not of
sufficient merit for holding the Viva Voce examination
and the candidate be declared to have failed and
not eligible for award of Ph. D./M. Phil degree
or an advise may be issued to the candidate for
amendments for resubmission.
The recommendations made by the examiners shall
be implemented.
Finally, each examiner shall submit his/her report
to the Rector and make one of the following recommendations:
i. that the candidate be declared to have passed
the examination;
ii. that the candidate be declared to have passed
the examination when he/she resubmits his/her
thesis incorporating corrections to be indicated
by the examiner to the satisfaction of the supervisor.
Acceptance or Rejection of Thesis
The BASR after taking into account the recommendation
of the viva voce examiners will:
i. Recommend that the degree be awarded
ii. Recommend that the degree be not awarded;
The candidate shall be admitted to the Ph.D. degree
in relevant discipline provided that he/she has
been declared to have passed the Viva Voce examination
in accordance with these regulations. In case
his/her thesis has been “Highly Commended” the
fact shall be recorded on the degree.
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